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OBJECTIVE To determine and evaluate the simultaneous use of multiple drugs in elderly people (aged > or = 65 years). DESIGN Cohort study. SETTING Region Rijnstreek, the Netherlands. METHOD In 200 consecutive persons who were evaluated for admission to a hospice or a nursing home, and who used > or = 5 drugs simultaneously, the drug use was determined(More)
OBJECTIVE To investigate the characteristics of general practitioners' patients given the diagnosis of 'surmenage' (French for 'nervous breakdown'). DESIGN Descriptive. SETTING General practices in Almere, the Netherlands. METHOD Four groups of general practice attenders were selected based on the general practitioners' diagnosis: a group of surmenage(More)
Case studies as weekly published in the New England Journal of Medicine are analysed using the computer programme Medwise. The programme covers more than 3,500 disease profiles. After entering clinical data on all patients described in 1986 and 1987, the diagnostic outcome was compared with the results of the clinicians and with the eventual(More)