K. G. Kjellin

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The CSF proteins have previously been very little investigated in the cerebellar syndrome of chronic alcoholism and in essential tremor. Such studies have been carried out more thoroughly by electrophoretic methods in Parkinson's disease but generally with normal results. In the present investigation the CSF proteins were examined by isoelectric focusing(More)
Isotachophoresis of CSF proteins seems to be a very promising method. Very small CSF samples, a few mul of concentrated and 15-30 mul of unconcentrated CSF, can be quickly analysed (30-60 min), and the results immediately obtained on a recorder. Using unconcentrated CSF, losses due to concentration procedures, are avoided. Low-molecular weight compounds,(More)
Peripheral neuropathy has been described in malignant plasma cell dyscrasias such as multiple myeloma and Waldenstöm's macroglobulinaemia. Since it is not known whether the neuropathy is related to the plasma cell disorder or is a paramalignant phenomenon, 21 consecutive out-patients with benign monoclonal gammopathy (BMG) were analysed for peripheral(More)
Spectrophotometric examinations were performed on cerebrospinal and subdural fluids in subacute (five patients) and chronic (20 patients) subdural haematomas, with special reference to the diagnostic aid of CSF spectrophotometry. Spectrophotometric xanthochromia of haemorrhagic origin was found in all CSFs examined, while definite visible xanthochromia was(More)
Thin-layer IEF, due to its extremely high resolving capacity, has been found to be quite valuable for CSF protein examinations, one important advantage of the technique being its excellent capacity for separation of immunoglobulins. The CSF and serum proteins of 230 patients with clinically verified or probable MS and 20 subjects with optic neuritis were(More)
Computer assisted axial tomography was performed in 32 patients with clinically possible cerebrovascular lesions. Decreased absorption as a sign of infarction was found in 15, increased absorption as a sign of hemorrhage in 7 cases. In another 7 cases, diagnosed as hemorrhagic infarction, a simultaneous occurrence of increased and decreased absorption(More)
The CSF gamma-globulin patterns found by electrofocusing in multiple sclerosis can be classified into five (a-e) mean patterns, where the individual bands lie very close together. However, in some patients with verified or probable multiple sclerosis conspicuous bands are found. The electrofocusing patterns from 28 such cases were compared with those(More)