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The intracellular translocation of protein kinase C (PKC) from the soluble to the membranous fraction has been shown previously to correlate with biological activity of phorbol esters in several(More)
12-O-tetradecanoylphorbol-13-acetate (TPA)-induced changes in cytoplasmic pH, cytoplasmic Ca2+-concentration, rate of DNA synthesis, and concentration and activity of protein kinase C (PKC) were(More)
The organelles in two human tumour cell lines in culture - U-937 and K-562 - involved in the receptor mediated endocytosis (RME) of transferrin (Tf) were studied after isolation from homogenates by(More)