Learn More
We have investigated the origin and nature of chromosome spatial order in human cells by analyzing and comparing chromosome distribution patterns of normal cells with cells showing specific chromosome numerical anomalies known to arise early in development. Results show that all chromosomes in normal diploid cells, triploid cells and in cells exhibiting(More)
We tested the hypothesis that deletion of adenylyl cyclase type V (ACV) would be associated with decreased left ventricular (LV) contractile function and responsiveness to β–adrenergic receptor (βAR) stimulation. Absence of cardiac ACV expression was confirmed by RT–PCR and immunoblotting in ACV–deleted mice (ACV -/-). Compared to sibling mice with normal(More)
This study examined the role of estrogen receptor (ER) beta during mouse femoral fracture healing by employing ER knockout (KO) mice. The fracture healing in KO mice was enhanced in the early stage of neovascularization and the middle stage of endochondral ossification. This study was conducted to examine the role of ER beta during fracture healing. Female(More)
PHB (poly-3-hydroxybutyric acid) is a thermoplastic polyester synthesized by Ralstonia eutropha and other bacteria as a form of intracellular carbon and energy storage and accumulated as inclusions in the cytoplasm of these bacteria. The degradation of PHB by fungi from samples collected from various environments was studied. PHB depolymerization was tested(More)
Presents the kinematic analysis of a three degree-of-freedom (DOF) spherical motor which presents some attractive features by combining pitch, roll, and yaw motion in a single joint. Besides being a compact design, the spherical motor possesses no gears or linkages and has no singularities within its workspace. The spherical motor presented operates on the(More)
The behavior characterizing choice response decision-making was studied in monkeys to provide background information for ongoing neurophysiological studies of the neural mechanisms underlying saccadic choice decisions. Animals were trained to associate a specific color from a set of colored visual stimuli with a specific spatial location. The visual stimuli(More)
The regulation of megakaryocytic differentiation is poorly understood. Using K562 cells, which can partly recapitulate the process in response to phorbol 12-myristate 13-acetate (PMA), we performed microarray-based gene expression profiling to identify genes that play significant roles in megakaryopoiesis. Here, we describe the function of FosB, an AP-1(More)
The aim of this study was to elucidate the anatomical location of nerve entry points of Flexor digitorum profundus (FDP) and its implications for non-surgical neurolysis. A total of 21 amputated forearms of 11 Korean fresh cadavers were dissected. Two transverse x-axes joined the medial and lateral epicondyles and the radial and ulnar styloid processes. The(More)
Safety-critical systems related to the railway communications are currently undergoing changes. Mechanical and electro-mechanical devices are being replaced by programmable electronics that are often controlled remotely via communication networks. Therefore designers and operators now not only have to contend with component failures and user errors, but(More)
  • 1