K De Schryver-Kecskemeti

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The rabbit hydronephrotic kidney (HNK) is a model of renal inflammation characterized by a marked increase in arachidonic acid metabolism which is temporally associated with an inflammatory cell influx into the injured tissue. The HNK exhibits an exaggerated elaboration of eicosanoids ex vivo in response to inflammatory agonists (bradykinin and the(More)
Tissue culture methods were used to study the gastrin-producing cells isolated from the pyloric antral mucosa of rats. Cultures were maintained for up to 7 days. Gastrin cells were identified by means of immunofluorescent and unlabeled antibody-enzyme techniques. The tissue culture medium was monitored for basal gastrin secretion. In addition, stimulation(More)
alpha 1-Antitrypsin (alpha 1-AT) is considered a typical plasma protein and a prototype of the serine proteinase inhibitor (serpin) family. It is synthesized in hepatocytes and, to a lesser extent, in macrophages. In this study we show that the alpha 1-AT gene is also expressed in human intestine and in a human colonic epithelial tumor cell line, Caco2. A(More)
Tissue lesions similar to those in human myospherulosis were reproduced in experimental animals and studied by light and electron microscopy. The lesions were produced by the use of petrolatum-based antibiotic ointments. These ointments, which are marketed as nonsterile products, are similar to those used for hemostatic packing in otolaryngologic surgery.(More)
An electronmicroscopic study of a human case of myospherulosis, which involved the nose and maxillary sinus, is reported. Large parent bodies limited by a thick electron-dense wall, enclosing variable numbers of spherules, were seen in cystic tissue spaces or adjacent connective tissue. Free spherules and shrunken degenerative forms were present as well.(More)
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