K. B. Parnham

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Small animal imaging relies on cone-beam reconstruction geometries to achieve high spatial resolution for both microSPECT and microCT. However, normal circular-orbit cone-beam geometries offer a restricted field of view which for microSPECT has nonuniform sensitivity and spatial resolution. These limitations can be addressed by using a more complex detector(More)
This paper will report on additional studies undertaken on a novel electrode geometry, referred to as CAPture technology, wherein the cathode is extended up the sides of a planar CdZnTe detector. The initial presentation of this development focused on a single geometry, and a simple mechanism was proposed to explain the improved performance. In this(More)
A second-generation, tri-modality instrument, comprising PET, SPECT, and CT subsystems, for pre-clinical imaging is described. Significant improvements have been made in each of the modalities as well as the integrated computer system. The SPECT system uses up to four CZT detectors with multiple pinhole apertures for each head, thereby increasing count(More)
The interest in the use of CdZnTe room-temperature, solid-state detectors for Nuclear Medicine applications continues to grow. Efforts are underway at several companies and institutes to develop CdZnTe detector systems to compete with existing scintillator-based Large Field of View (LFOV) gamma cameras. eV PRODUCTS is focusing on the development of Small(More)
Small animal microSPECT systems require high resolution and efficiency to faithfully image biodistributions of molecular reporters and radiopharmaceuticals in a short time. Because of their variable magnification, pinhole and multipinhole cameras are particularly well suited for small animal imaging systems. These cameras nonetheless require a high degree(More)
We have developed and tested a pixelated detector for pinhole SPECT. The 80/spl times/80 detector has a pixel size of 2.5/spl times/2.5 mm/sup 2/ and incorporates the room-temperature solid-state semiconductor CdZnTe which offers direct charge conversion and good stopping power for radionuclides used for small animal SPECT. To optimize low energy photon(More)
Cadmium zinc telluride or CZT cameras offer dual-isotope imaging capabilities impossible to duplicate using any other pre-clinical molecular imaging system. This new technology will enable the investigation of multiple biological processes in parallel and open new areas in research and drug development. The dual-isotope capability is due to the improved(More)
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