Jyun-ichi Koseki

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It has already been reported that 3-(indol-2-yl)quinoxalin-2-ones have a potent inhibitory effect on the growth of tumor cells based on anti-angiogenesis activity. We have also carried out a structure-activity relationship (SAR) study of 3-(indol-2-yl)quinoxalin-2-ones, which showed a potent inhibitory activity toward the vascular endothelial growth factor(More)
as an anti-angiogenesis agent by Ladouceur et al. These compounds have a potent inhibitory effect on the growth of tumor cells with angiogenesis activity. We have also carried out a structure–activity relationship (SAR) study of 3-(indol2-yl)quinoxalin-2-ones, which showed a potent inhibitory activity toward the VEGF-induced proliferation of human mesangial(More)
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