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Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
- Rosalind A. Eeles, Ali Amin Al Olama, +141 authors Douglas F. Easton
- Nature Genetics
- 2013
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a custom Illumina… (More)
- Rosalind A. Eeles, Zsofia Kote-Jarai, +98 authors Douglas F. Easton
- Nature Genetics
- 2009
Prostate cancer (PrCa) is the most frequently diagnosed cancer in males in developed countries. To identify common PrCa susceptibility alleles, we previously conducted a genome-wide association study… (More)
- Zsofia Kote-Jarai, Ali Amin Al Olama, +128 authors Rosalind A. Eeles
- Nature Genetics
- 2011
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa and previously reported the results of… (More)
- Radhika Patnala, Judith Ann Clements, Jyotsna Batra
- BMC Genetics
- 2012
The candidate gene approach has been a pioneer in the field of genetic epidemiology, identifying risk alleles and their association with clinical traits. With the advent of rapidly changing… (More)
- Siddhartha P. Kar, Jonathan Beesley, +220 authors Diether Lambrechts
- Cancer discovery
- 2016
UNLABELLED
Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association (GWA) studies.… (More)
- Jiyuan An, John Lai, Atul Sajjanhar, Jyotsna Batra, Chenwei Wang, Colleen C. Nelson
- Bioinformatics
- 2015
SUMMARY
Circos plots are graphical outputs that display three dimensional chromosomal interactions and fusion transcripts. However, the Circos plot tool is not an interactive visualization tool, but… (More)
- Ali Amin Al Olama, Sara Benlloch, +62 authors Douglas F. Easton
- Cancer epidemiology, biomarkers & prevention : a…
- 2015
BACKGROUND
Genome-wide association studies have identified multiple genetic variants associated with prostate cancer risk which explain a substantial proportion of familial relative risk. These… (More)
- Felicity A. Lose, Christina M Nagle, +10 authors Amanda B Spurdle
- Gynecologic oncology
- 2010
OBJECTIVES
We sought to evaluate the effect of polymorphisms in the VEGF (Vascular Endothelial Growth Factor) gene on overall survival in ovarian cancer patients.
METHODS
A sample of 319 women… (More)
- Jyotsna Batra, Olivia L Tan, +5 authors Amanda B Spurdle
- International journal of gynecological cancer…
- 2010
INTRODUCTION
Kallikrein-related peptidase 10 (KLK10) overexpression is a predictor of poor disease outcome in women with late-stage ovarian cancer. We aimed to identify whether KLK10 overexpression… (More)
- Jyotsna Batra, Tracy O'Mara, Radhika Patnala, Felicity A. Lose, Judith Ann Clements
- Biological chemistry
- 2012
The Kallikrein ( KLK ) gene locus encodes a family of serine proteases and is the largest contiguous cluster of protease-encoding genes attributed an evolutionary age of 330 million years. The KLK… (More)