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A number of dermal toxicological studies using TiO2 nanoparticles exist which are based on the study of various animal models like mice, rabbits etc. However, a well-defined study is lacking on the dermal toxic effects of TiO2 nanoparticles on rats, which are the appropriate model for systemic absorption study of nanoparticles. Furthermore, toxicity of TiO2… (More)
Titanium dioxide (TiO2) is one of the most widely used nanoparticles. Synthesized TiO2 nanoparticles (approximately 20 nm) at a concentration of 42 mg/kg bw induced biochemical perturbations in Wistar rats. TiO2 nanoparticles exhibited hepatic and renal toxicity in Wistar rats.