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In clinical studies of antidepressants, the Hamilton Depression Rating Scale (HAMD) total score has been the gold standard instrument for establishing and comparing the efficacy of new treatments. However, the HAMD is a multidimensional measure, which may reduce its ability to detect differences between treatments, in particular, changes in core symptoms of(More)
A large number of legacy and Third-Party-Organization (TPO) provided clinical trial statistical analysis output files stored in SAS Drug Development (SDD) are in .txt (text) format. Because of many advantages of rich text format (RTF) files compared with text files, it's a common task to convert these files from text format to RTF to meet the submissions,(More)
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