Jyoti Bala Gupta

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Studies in rodent epilepsy models suggest that GABAergic interneuron progenitor grafts can reduce hyperexcitability and seizures in temporal lobe epilepsy (TLE). Although integration of the transplanted cells has been proposed as the underlying mechanism for these disease-modifying effects, prior studies have not explicitly examined cell types and synaptic(More)
BACKGROUND Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a serious pathogen in several regions in the United States. It is unclear which populations are at high risk for the emergence of these strains. METHODS All unique patient isolates of S. aureus were collected from hospitals in Brooklyn, NY over a three-month period.(More)
The sulfonylurea glibenclamide is a relatively potent inhibitor of the CFTR Cl(-) channel. This inhibition is thought to be via an open channel block mechanism. However, nothing is known about the physical nature of the glibenclamide-binding site on CFTR. Here we show that mutations in the pore-forming 6th and 12th transmembrane regions of CFTR affect block(More)
International Refereed Research Journal ■ w ww ww w. .r re es se ea ar rc ch he er rs sw wo or rl ld d.. ABSTRACT The research work in data mining has achieved a high attraction due to the importance of its applications This paper addresses some theoretical and practical aspects on Exploiting Data Mining Techniques for Improving the Efficiency of Time(More)
The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel contains 12 membrane-spanning regions which are presumed to form the transmembrane pore. Although a number of findings have suggested that the sixth transmembrane region plays a key role in forming the pore and determining its functional properties, the role of other transmembrane(More)
Wireless mesh networks (WM Ns) have achieved significant development because of fast deployment, easy maintenance and low investment compared with traditional wireless networks. Since WM Ns are typically used as wireless backbones, they have the nature that the wireless communication is not constant. Hence, it is important to defend them against link or(More)
OBJECTIVES Quorum-sensing systems regulate expression of several virulence factors and may affect the MexAB-OprM efflux system in Pseudomonas aeruginosa. This study investigated the relationship between two quorum-sensing systems, efflux pump MexAB-OprM expression and antimicrobial resistance in 33 clinical isolates of P. aeruginosa. METHODS Expression of(More)
Point mutations within the pore region of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel have previously been shown to alter the selectivity of the channel between different anions, suggesting that part of the pore may form an anion 'selectivity filter'. However, the full extent of this selectivity filter region and the(More)
Cone beam computed tomography (CBCT) scanners for the oral and maxillofacial region were pioneered in the late 1990s independently by Arai et al. in Japan and Mozzo et al. CBCT has a lower dose of radiation, minimal metal artifacts, reduced costs, easier accessibility, and easier handling than multislice computed tomography (MSCT); however, the latter is(More)
Multiplier is the most commonly used circuit in the digital devices. Multiplication is one of the basic functions used in digital signal processing. Most high performance DSP systems rely on hardware multiplication to achieve high data throughput. There are various types of multipliers available depending upon the application in which they are used. Full(More)