Jutta Rickers-Haunerland

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The induction of cardiac FABP expression by long‐chain fatty acids was measured in cultured rat myoblasts, myotubes and adult cardiomyocytes. With quantitative RT‐PCR techniques, the primary transcription product of the FABP gene and the mature mRNA were measured. Incubations of 30 min resulted in a larger than 2‐fold increase of the primary transcript in(More)
The retinas of many vertebrates have cone photoreceptors that express multiple visual pigments. In many of these animals, including humans, the original cones to appear in the retina (which express UV or blue opsin) may change opsin types, giving rise to new spectral phenotypes. Here we used microspectrophotometry and in situ hybridization with cDNA probes(More)
The gene coding for rat heart fatty acid-binding protein (FABP), along with 1.2 kb of its 5'-untranscribed region, was amplified by PCR, cloned and sequenced. As in other FABP genes, the coding sequence is interrupted by three introns of 3.4, 1.4 and 1.1 kb, respectively. Fluorescence in situ hybridization mapping revealed that the gene is located on(More)
In vertebrate and invertebrate muscles, the expression of fatty acid binding proteins (FABP) is induced by long chain fatty acids. To identify the fatty acid response elements that mediate this up-regulation, the gene of the FABP expressed in locust flight muscle was cloned, and its upstream sequences analyzed for potential regulatory elements. Comparison(More)
The heart is the most fatty acid-dependent muscle in mammals, but flight muscles of birds and insects encounter even higher rates of fatty acid oxidation. The amount of the muscle fatty acid binding protein (H-FABP) found in these muscle reflects their metabolic activities, and increased fatty acid metabolism in endurance exercise increases FABP expression(More)
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