Justus W Hilpert

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The introduction of automated oscillometric blood pressure monitors was the basis for today's widespread use of blood pressure self-measurement. However, in atrial fibrillation, there is a controversial debate on the use of oscillometry because there is a high variability of heart rate and stroke volume. To date, the accuracy of oscillometric blood pressure(More)
PERSISTENT or uncontrolled bleeding is one of the most feared consequences of any surgical procedure. Numerous factors can contribute to its etiology. Among these, both inherited and acquired disorders of coagulation and/or thrombocyte function need to be taken into account. Acquired hemophilia can be caused by antibodies to coagulation factors. Antibodies(More)
Vancomycin (VAN) dosing requires adjustment to renal function, which is often estimated using the Cockcroft-Gault formula; however, its precision is poor in Intensive Care Unit (ICU) patients. VAN clearance (CL(Van)) during continuous infusion was prospectively determined in 25 ICU patients [14 male, 11 female; age range 31-82 years; body mass index (BMI)(More)
Das Angelman-Syndrom (AS) ist eine seltene Erkrankung mit einer Inzidenz von 1:10.000 bis 1:40.000, der ein fehlerhaftes genetisches „imprinting“ im Chromosomensegment 15q11–q13 zugrunde liegt. Ergebnisse experimenteller Studien legen nahe, dass davon der γ-Aminobuttersäure-A- (GABAA-)Rezeptor, aber auch der N-Methyl-D-Aspartat- (NMDA-) oder der(More)
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