Justus D Adamson

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Margin reduction for prostate radiotherapy is limited by uncertainty in prostate localization during treatment. We investigated the feasibility and accuracy of measuring prostate intrafraction motion using kV fluoroscopy performed simultaneously with radiotherapy. Three gold coils used for target localization were implanted into the patient's prostate gland(More)
PURPOSE To evaluate the feasibility of adaptive planning using positron emission tomography-computed tomography (PET-CT) in locally advanced non-small cell lung cancer. METHODS AND MATERIALS Patients with locally advanced non-small cell lung cancer receiving definitive radiation therapy (RT) were eligible. Initial planning PET-CT was performed and a(More)
PURPOSE To evaluate the ability of rectal filling, bladder filling, and prostate localization from pre- and posttreatment volumetric imaging to predict prostate intrafraction motion. METHODS AND MATERIALS Pre- and posttreatment cone beam computed tomography images (CBCTs) and intrafractional kV fluoroscopy were acquired at each fraction for 20 prostate(More)
PURPOSE Several recent series evaluating external beam accelerated partial breast irradiation (PBI) have reported adverse cosmetic outcomes, possibly related to large volumes of normal tissue receiving near-prescription doses. We hypothesized that delivery of external beam PBI in a single fraction to the preoperative tumor volume would be feasible and(More)
PURPOSE To describe prostate intrafraction motion using kilovoltage fluoroscopy at treatment delivery for a hypofractionated radiotherapy protocol. METHODS AND MATERIALS Kilovoltage images were acquired during treatment delivery, as well as pre- and posttreatment cone-beam computed tomography (CBCT) for each fraction of 30 patients, totaling 571 fractions(More)
PURPOSE To quantify the dosimetric effect and margins required to account for prostate intrafractional translation and residual setup error in a cone beam computed tomography (CBCT)-guided hypofractionated radiotherapy protocol. METHODS AND MATERIALS Prostate position after online correction was measured during dose delivery using simultaneous kV(More)
We propose a method to incorporate independent verification of gantry angle for electronic portal imaging device (EPID)-based pre-treatment quality assurance (QA) of clinical volumetric modulated arc therapy (VMAT) plans. Gantry angle is measured using projections in the EPID of a custom phantom placed on the couch and the treatment plan is modified so as(More)
Volumetric modulated arc therapy (VMAT) is a relatively new treatment modality for dynamic photon radiation therapy. Pre-treatment quality assurance (QA) is necessary and many efforts have been made to apply electronic portal imaging device (EPID)-based IMRT QA methods to VMAT. It is important to verify the gantry rotation speed during delivery as this is a(More)
OBJECTIVE Our purpose was to address challenges associated with single-isocenter radiosurgery for multiple intracranial targets (SIRMIT) including increased sensitivity to rotational uncertainties (resulting from distance of the targets from isocenter) as well as potential for decreased plan quality from larger multileaf collimator width >4 cm from(More)
PURPOSE To investigate potential benefits of adaptive strategies for managing prostate intrafractional uncertainties when interfraction motion is corrected online. METHODS AND MATERIALS Prostate intrafraction motion was measured using kV fluoroscopy during MV delivery for 571 fractions from 30 hypofractionated radiotherapy patients. We evaluated trending(More)