Eosinophil responses during COVID-19 infections and coronavirus vaccination
- A. Lindsley, Justin T. Schwartz, M. Rothenberg
- Medicine, BiologyJournal of Allergy and Clinical Immunology
- 25 April 2020
Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis
- R. McCaffrey, Justin T. Schwartz, L. Allen
- BiologyJournal of Leukocyte Biology
- 1 October 2010
Several type A and type B Ft strains are used to demonstrate that Ft‐mediated NADPH oxidase inhibition is more complex than appreciated previously, and data strongly suggest that this is a central aspect of virulence.
Natural IgM Mediates Complement-Dependent Uptake of Francisella tularensis by Human Neutrophils via Complement Receptors 1 and 3 in Nonimmune Serum
- Justin T. Schwartz, Jason Barker, M. E. Long, Justin W Kaufman, J. McCracken, L. Allen
- Biology, MedicineJournal of Immunology
- 15 September 2012
The data provided provide fundamental insight into mechanisms of F. tularensis phagocytosis and support a model whereby natural IgM binds to surface capsular and O-Ag polysaccharides of F., and initiates the classical complement cascade via C1q to promote C3 opsonization of the bacterium and phagocytes via CR3 and either CR1 or CR4 in a phagocyte-specific manner.
Role of urease in megasome formation and Helicobacter pylori survival in macrophages
- Justin T. Schwartz, L. Allen
- BiologyJournal of Leukocyte Biology
- 1 June 2006
A role for urease and Urease‐derived ammonia in megasome formation and Hp survival is indicated and it is indicated that intracellular survival of mutant organisms was impaired significantly.
Francisella tularensis Inhibits the Intrinsic and Extrinsic Pathways To Delay Constitutive Apoptosis and Prolong Human Neutrophil Lifespan
- Justin T. Schwartz, Jason Barker, Justin W Kaufman, Drew C. Fayram, J. McCracken, L. Allen
- Biology, MedicineJournal of Immunology
- 1 April 2012
It is demonstrated that F. tularensis profoundly impairs constitutive neutrophil apoptosis via effects on the intrinsic and extrinsic pathways, and thereby defines a new aspect of innate immune evasion by this organism.
Francisella tularensis Alters Human Neutrophil Gene Expression: Insights into the Molecular Basis of Delayed Neutrophil Apoptosis
- Justin T. Schwartz, S. Bandyopadhyay, L. Allen
- BiologyJournal of Innate Immunity
- 14 September 2012
The data strongly suggest that antiapoptotic and prosurvival mechanisms collaborate to sustain the viability of F. tularensis--infected neutrophils.
An Approach to the Evaluation of Persistent Hypereosinophilia in Pediatric Patients
- Justin T. Schwartz, P. Fulkerson
- MedicineFrontiers in Immunology
- 3 September 2018
The differential diagnosis for pediatric HE is discussed, highlighting etiologies that are more prevalent within the pediatric population, and a directed approach to the diagnostic evaluation of children with HE will be discussed.
Pediatric Hypereosinophilia: Characteristics, Clinical Manifestations, and Diagnoses.
- D. Burris, C. Rosenberg, P. Fulkerson
- MedicineJournal of Allergy and Clinical Immunology: In…
- 1 February 2018
Eosinophil progenitor levels correlate with tissue pathology in pediatric eosinophilic esophagitis.
- Justin T. Schwartz, D. Morris, M. Collins, M. Rothenberg, P. Fulkerson
- MedicineJournal of Allergy and Clinical Immunology
- 1 March 2019
Monitoring Eosinophilic Esophagitis Disease Activity with Blood Eosinophil Progenitor Levels.
- A. Henderson, Adam Z. Magier, P. Fulkerson
- MedicineJournal of Pediatric Gastroenterology and…
- 12 December 2019
This study suggests that blood EoP levels may be used as a biomarker to detect active EoE disease in patients undergoing food trials and potentially reduce the need for repeated endoscopies.
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