Justin T Douglas

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This article presents equations for the estimation of horizontal strong ground motions caused by shallow crustal earthquakes with magnitudes M w ≥ 5 and distance to the surface projection of the fault less than 100 km. These equations were derived by weighted regression analysis, used to remove observed magnitude-dependent variance, on a set of 595(More)
Attenuation of increased endocannabinoid signaling with a CB1R neutral antagonist might offer a new therapeutic direction for treatment of alcohol abuse. We have recently reported that a monohydroxylated metabolite of the synthetic aminoalkylindole cannabinoid JHW-073 (3) exhibits neutral antagonist activity at CB1Rs and thus may serve as a promising lead(More)
Matrix metalloproteinase 2 (MMP-2) contains three fibronectin type II (col) modules that contribute to its collagen specificity. We observed that the CD spectra of the separate col modules account for the CD and temperature profiles of the in-tandem col-123 construct. Thus, to the extent of not significantly perturbing the secondary structure and thermal(More)
This article presents equations for the estimation of vertical strong ground motions caused by shallow crustal earthquakes with magnitudes M w ≥ 5 and distance to the surface projection of the fault less than 100 km. These equations were derived by weighted regression analysis, used to remove observed magnitude-dependent variance, on a set of 595(More)
Lanthanide (Ln3+) doping in alumina has shown great promise for stabilizing and promoting desirable phase formation to achieve optimized physical and chemical properties. However, doping alumina with Ln elements is generally accompanied by formation of new phases (i.e. LnAlO3, Ln2O3), and therefore inclusion of Ln-doping mechanisms for phase stabilization(More)
As part of our continuing efforts toward more fully understanding the structure-activity relationships of the neoclerodane diterpene salvinorin A, we report the synthesis and biological characterization of unique cycloadducts through [4+2] Diels-Alder cycloaddition. Microwave-assisted methods were developed and successfully employed, aiding in(More)
  • Chan Woo Huh, Gagandeep K Somal, +4 authors Jeffrey Aubé
  • 2009
A series of domino reactions in which the intramolecular Schmidt reaction is combined with either a Sakurai reaction, an aldol reaction, or both is reported. The Sakurai reaction of an allylsilane with an azido-containing enone under Lewis acidic conditions followed by protonation of the resulting titanium enolate species allowed for a subsequent(More)
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