Justin M Milligan

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Through the combined efforts of neurosurgeons, head and neck surgeons, and craniofacial surgeons, the standard transbasal approach to the frontal fossa has been modified to include removal of the orbital roofs, nasion, and ethmoid sinuses. This approach has been combined further with facial disassembly procedures to provide extensive midline exposure to the(More)
We recently reported that the 25 amino acid peptide xenin caused reduced feed intake when centrally injected in chicks. The present study was designed to explore possible mechanisms of the xenin-induced anorexigenic response in chicks. In Experiments 1 and 2, chicks were implanted with cannulas and xenin injections were made directly into the ventromedialis(More)
BACKGROUND AND OBJECTIVES A filter (PRF1) designed to remove abnormal prion proteins from red-cell units has been developed. The purpose of this study was to evaluate the quality of red cells produced using this device. MATERIALS AND METHODS Leucocyte-depleted red-cell units (CPD, CPD-A1 and CPD/SAGM) processed according to standard UK practices were(More)
Prenatal karyotyping was performed on 136 patients because of one or more abnormalities detected on ultrasound. A total of 188 specimens was obtained which included fetal blood, amniotic fluid and chorionic villus. In 52 patients a second or 'backup' sample was obtained and in 100% cytogenetic analysis was successful. In contrast, failure to obtain a result(More)
Improvements in ultrasound technology have resulted in an increasing number of requests for prenatal chromosome testing because of fetal abnormalities detected in utero. Between January 1990--January 1991, 388 tissue samples were referred to our laboratory for cytogenetic analysis, of which 202 were amniotic fluids samples, 157 chorionic villus biopsies and(More)
BACKGROUND Clival chordomas are difficult tumors to treat, particularly when they have already grown beyond the confines of the clivus. PATIENT We report the case of a 52-year-old man with a clival mass consistent with a chordoma with a prominent extension into the right middle fossa. At the patient's request, he underwent a simple endonasal biopsy to(More)
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