Justin Hoffman

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Protease-activated receptor-2 (PAR2) is a G-Protein Coupled Receptor (GPCR) activated by proteolytic cleavage to expose an attached, tethered ligand (SLIGRL). We evaluated the ability for lipid-tethered-peptidomimetics to activate PAR2 with in vitro physiological and Ca2+ signaling assays to determine minimal components necessary for potent, specific and(More)
As members of the Dissertation Committee, we certify that we have read the dissertation prepared by Dipti Vilas Tillu entitled " AMPK AS A NOVEL TARGET FOR TREATMENT OF NEUROPATHIC AND POST-SURGICAL PAIN " and recommend that it be accepted as fulfilling the dissertation requirement for Final approval and acceptance of this dissertation is contingent upon(More)
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