Justin Carlstrom

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Aggressive otologic management has been recommended for children with cleft palate because of the almost universal occurrence of otitis media with effusion (OME) in these children and the association of OME with hearing loss and possible language, cognitive, and academic delays. In this study, 28 children with cleft palate and 29 noncleft children were seen(More)
Positive end-expiratory pressure (PEEP) is used in the treatment of infants with respiratory distress syndrome (RDS) to prevent atelectasis, recruit alveolar space and return the functional residual capacity (FRC) toward normal volumes. This study determined the FRC range of 15 prematurely born infants with RDS receiving PEEP. Ventilator settings were(More)
Diets high in quercetin may decrease the risk of developing cardiovascular disease. We tested whether quercetin delays or reduces the severity of hypertension, vascular dysfunction, or cardiac hypertrophy in the spontaneously hypertensive rat (SHR). Normotensive, 5-wk-old SHR consumed standard (n = 18) or quercetin-supplemented diet (1.5 g quercetin/kg(More)
Quercetin (Q), a flavonoid found in berries and onions, can reduce blood pressure in hypertensive animals and inhibit signal transduction pathways in vitro that regulate cardiac hypertrophy. We hypothesized that quercetin could prevent cardiovascular complications in rats with abdominal aortic constriction (AAC). Rats consumed standard or Q-supplemented(More)
The purposes of this study were to determine the effects of positive end-expiratory pressure (PEEP) and end-expiratory lung volume on systemic blood flow, whether PEEP levels yielding maximum systemic oxygen transport are associated with maximum lung compliance, and the effects of end-expiratory lung volume on pulmonary resistance to gas flow, in an animal(More)
The objective of this research was to determine the oxygen consumption of newborn infants with respiratory distress syndrome in the first 4 days of life. Serial determinations of oxygen consumption were made in 14 infants with respiratory distress syndrome receiving positive end-expiratory pressures. The mean (+/- SE) oxygen consumption determined at 24,(More)
Standard techniques for measuring pulmonary resistance (RP) to gas flow in newborn infants yield results that are widely dispersed and difficult to interpret. The purpose of this study is to describe and evaluate a new improved method for determining RP which utilizes a sinusoidal pressure wave generator. Measurements of respiratory flow rate and(More)
Since high frequency jet ventilation (HFJV) relies on lung mechanics for the passive removal of expiratory gas, one would predict that the time allowed for exhalation would have serious effects on cardiopulmonary function. To document these effects we lavaged the lungs of ten cats with 30 ml/kg of saline six times, then sampled arterial and venous blood(More)
The purpose of this study was to demonstrate that ventilation of rabbit lungs (whose mechanics are similar to those of human infants) at rapid rates will lead to large alterations in tracheal airway pressures, tidal volume, and functional residual capacity (FRC) with only minor changes in arterial blood gases. Thirteen rabbits were ventilated at rates of(More)
This study determined the effects of end-expiratory pressures (EEP) and alterations in end-expiratory lung volume (EELV) on lung compliance (CL) and pulmonary resistance to gas flow (RP) in 20 cats with normal and edematous lungs. EELV was varied using EEP ranging from -8 to +10 cm H2O. Negative EEP was used to decrease EELV of the healthy lung causing CL(More)