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The regular array of distally pointing hairs on the mature Drosophila wing is evidence for the fine control of Planar Cell Polarity (PCP) during wing development. Normal wing PCP requires both the Frizzled (Fz) PCP pathway and the Fat/Dachsous (Ft/Ds) pathway, although the functional relationship between these pathways remains under debate. There is strong(More)
The Drosophila wing is a primary model system for studying the genetic control of epithelial Planar Cell Polarity (PCP). Each wing epithelial cell produces a distally pointing hair under the control of the Frizzled (Fz) PCP signaling pathway. Here, we show that Fz PCP signaling also controls the formation and orientation of ridges on the adult wing(More)
The polarity of hairs on the adult Drosophila wing provides information about the planar cell polarity (PCP) signaling events that occur during pupal wing development. We have recently shown that PCP signaling also determines the orientation of cuticle ridges that traverse the surface of the adult wing membrane; a feature we call the wing membrane(More)
A custom FPGA-based, 1U CubeSat form-factor reconfigurable computing development platform has been designed and built for the purpose of implementing and testing multicore and multiprocessor systems. The platform was designed to leverage the active partial reconfiguration and configuration readback capabilities of the Xilinx Virtex-6 device. This enables(More)
Thermal analysis was required in order to aid in the design and testing of a radiation tolerant computing (RTC) system using a radiation sensor. During development of the system, different test beds were employed in order to characterize the radiation sensor and its supporting electronic systems. The most common preliminary tests are high altitude balloon(More)
The Drosophila wing consists of a transparent wing membrane supported by a network of wing veins. Previously, we have shown that the wing membrane cuticle is not flat but is organized into ridges that are the equivalent of one wing epithelial cell in width and multiple cells in length. These cuticle ridges have an anteroposterior orientation in the anterior(More)
This paper describes the benchmarking of an FPGA-based computing system that uses partially reconfigurable tiles for real-time allocation of hardware resources. This system was developed for use in the aerospace industry in order to provide redundancy for fault mitigation and real-time hardware reallocation to reduce mass associated with separate functional(More)
Field Programmable Gate Arrays are an attractive platform for reconfigurable computing due to their inherent flexibility and low entry cost relative to custom integrated circuits. With modern programmable devices exploiting the most recent fabrication nodes, designs are able to achieve device-level performance and power efficiency that rivals custom(More)
— This paper describes research efforts to mitigate weaknesses in a TMR+spares radiation tolerant SRAM-based FPGA computer system. An existing 9-tile Microblaze architecture is reviewed and the desired improvements of fault-mitigated routing, fault location determination and performance enhancement via runtime-configurable hardware accelerators are(More)
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