Jurrien de Klerk

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The pyruvate dehydrogenase complex (PDHc) is a multienzyme complex consisting of three catalytic and two regulatory enzymes, as well as a less well defined subunit called protein X. PDHc deficiency is a common cause of congenital lactic acidosis. Most patients with PDH deficiency have a mutation in the α chain of the PDH E1 enzyme. Very few patients have(More)
This paper presents a runtime resource management scheme named Cache Balancer that improves the utilization of on-chip shared caches and reduces access latencies in chip multiprocessor systems. Cache Balancer incorporates an access rate based memory allocator that improves utilization of on-chip cache resources resulting in up to 60% lower contention at(More)
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