Jurgen Brockmöller

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To evaluate whether alterations in the multidrug-resistance (MDR)-1 gene correlate with intestinal MDR-1 expression and uptake of orally administered P-glycoprotein (PGP) substrates, we analyzed the(More)
The polymorphic arylamine N-acetyltransferase (NAT2; EC is supposed to be a susceptibility factor for several drug side effects and certain malignancies. A group of 844 unrelated German(More)
Foreign compound-metabolizing enzymes may modify the risk of chemically induced cancer. We wanted to examine enzymes with putative relevance in urinary bladder cancer using molecular genetic analyses(More)