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PTEN phosphatase is a potent tumor suppressor that regulates multiple cellular functions. In the cytoplasm, PTEN dephosphorylates its primary lipid substrate, phosphatidylinositol 3,4,5-trisphosphate, to antagonize the phosphatidylinositol 3-kinase (PI3K)/AKT signaling pathway. It has also become increasingly evident that PTEN functions in the nucleus and(More)
In this paper, we consider a risk model in which each main claim induces a delayed claim called a by-claim. The time of delay for the occurrence of a by-claim is assumed to be exponentially distributed. From martingale theory, an expression for the ultimate ruin probability can be derived using the Lundberg exponent of the associated nondelayed risk model.(More)
This paper considers the optimal investment strategy for an insurer under the criterion of mean-variance. The risk process is a compound Poisson process and the insurer can invest in a risk-free asset and multiple risky assets. This paper obtains the optimal investment policy using the stochastic linear quadratic (LQ) control theory with no-shorting(More)
In this paper, we consider the survival probability for a discrete semi-Markov risk model, which assumes individual claims are influenced by a Markov chain with finite state space and there is autocorrelation among consecutive claim sizes. Our semi-Markov risk model is similar to the one studied in Reinhard and Snoussi [1, 2] without the restriction imposed(More)
  • Xiaoli Su, C. K. Shum, +5 authors Yuchan Yi
  • IEEE Transactions on Geoscience and Remote…
  • 2018
Knowledge of interannual mass variations of the Antarctic ice sheet (AIS) associated with its surface mass change is important for correctly interpreting the long-term mass trend and evaluating the fidelity of surface mass balance from regional climate models. Here, we revisit the interannual anomalies of mass change from Gravity Recovery and Climate(More)