Junyang Wang

Learn More
Previous studies have indicated that interleukin-1 beta (IL-1 beta) is involved not only in immune modulation, but also in the modulation of pain in both the peripheral and central nervous systems. The current study investigated the expression of IL-1 beta in the brain of rats with spared nerve injury (SNI), using immunohistochemical technique. The results(More)
The pro-inflammatory cytokine tumor necrosis factor-α (TNF-α) is associated with the generation of inflammatory and neuropathic pain. The current study aims to investigate the expression of TNF-α in the brain of rats with spared nerve injury (SNI), a neuropathic pain model with the lesion of common peroneal and tibial nerves. Two weeks following SNI, the(More)
Spinocerebellar ataxia type 6 (SCA6) is caused by polyglutamine expansion in P/Q-type Ca2+ channels (Ca(v)2.1) and is characterized by predominant degeneration of cerebellar Purkinje cells. To characterize the Ca(v)2.1 channel with an SCA6 mutation in cerebellar Purkinje cells, we have generated knock-in mouse models that express human Ca(v)2.1 with 28(More)
Cabazitaxel-loaded human serum albumin nanoparticles (Cbz-NPs) were synthesized to overcome vehicle-related toxicity of current clinical formulation of the drug based on Tween-80 (Cbz-Tween). A salting-out method was used for NP synthesis that avoids the use of chlorinated organic solvent and is simpler compared to the methods based on emulsion-solvent(More)
BACKGROUND Streptomycetes attract a lot of attention in metabolic engineering and synthetic biology because of their well-known ability to produce secondary metabolites. However, the available constitutive promoters are rather limited in this genus. RESULTS In this work, constitutive promoters were selected from a pool of promoters whose downstream genes(More)
  • Junyang Wang, Eric, Finkelstein, Supervisor, Stewart Kearsley, Yousuf +1 other
  • 2014
Objectives: To understand the key factors guiding women's decision of whether or not to use breast and cervical cancer screening services (in order to determine how to cost effectively increase screening uptake in following conjoint). Methods: We conducted eight focus groups, with Singaporean women aged between 40 and 64 for breast cancer screening, and(More)
  • 1