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DYX1C1 and KIAA0319 have been two of the most extensively studied candidate genes for dyslexia given their important roles in the neuronal migration and neurite growth. The -3G > A in DYX1C1 and the 931C > T in KIAA0319 were of special interest for dyslexia but with inconsistent results. We performed a meta-analysis integrating case-control and(More)
PRIMARY OBJECTIVE To examine the hospitalization costs and discharge outcomes of US children with TBI and to evaluate a severity measure, the predictive mortality likelihood level. RESEARCH DESIGN Data from the 2006 Healthcare Cost and Utilization Project Kids' Inpatient Database (KID) were used to report the national estimates and characteristics of(More)
BACKGROUND There is little research which examines disability status and the employment decisions of the US immigrant working-age population. METHODS The 2007 American Community Survey data were analyzed to compare disabilities and employment characteristics between immigrant and US-born adults 18-64 years of age. Separate logistic regression models of(More)
OBJECTIVE To evaluate the definition of traumatic brain injury (TBI) in the National Electronic Injury Surveillance System (NEISS) and compare TBI case ascertainment using NEISS vs. ICD-9-CM diagnosis coding. METHODS Two data samples from a NEISS participating emergency department (ED) in 2008 were compared: (1) NEISS records meeting the recommended NEISS(More)
Children with disabilities are thought to have an increased risk of unintentional injuries, but quantitative syntheses of findings from previous studies have not been done. We conducted a systematic review and meta-analysis to assess whether pre-existing disability can increase the risk of unintentional injuries among children when they are compared to(More)
BACKGROUND Chronic conditions influence the outcomes of adult trauma patients, but no study has investigated the impact of chronic conditions among pediatric trauma patients. METHODS We performed a retrospective study using the 2009 Healthcare Cost and Utilization Project Kids' Inpatient Database (KID) to determine the prevalence of chronic conditions(More)
OBJECTIVE To evaluate the National Electronic Injury Surveillance System's (NEISS) comparability with a data source that uses ICD-9-CM coding. METHODS A sample of NEISS cases from a children's hospital in 2008 was selected, and cases were linked with their original medical record. Medical records were reviewed and an ICD-9-CM code was assigned to each(More)
Two hundred twenty-five SCD children have been enrolled in a study assessing the tolerability of hydroxyurea treatment. Mean age at inclusion was 9.2+/-4.4 years, median duration of treatment was 3.8 years. Ten and 75 patients have been treated respectively for more than 10 and 5 years. No severe side effect was related to hydroxyurea treatment, which was(More)
BACKGROUND There is evidence that regionalized trauma care and appropriate triage of major trauma patients improve patient outcomes. However, the national rate of undertriage and diagnoses of undertriaged patients are unknown. METHODS We used the 2010 Nationwide Emergency Department Sample to estimate the national rate of undertriage, identify the(More)
OBJECTIVE We aimed to investigate the patterns and risk factors of nonfatal injuries among rural mountain-area children in southwest China. METHODS A stratified sampling method was used to recruit rural children aged 8 to 17 years (mainly 9-14 years) from 7 schools. Self-reported injuries during the past 12 months and relevant concerns were collected from(More)