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  • Kyu Seo Cho, Junsu Lee, +6 authors Joanne M. Chung
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2001 (First Publication: 22 May 2001)
  • Phosphoinositide-dependent kinase-1 (PDK-1) is a central mediator of the cell signaling between phosphoinositide 3-kinase (PI3K) and various intracellular serine/threonine kinases includingContinue Reading
  • Johannes Voortman, Junsu Lee, +7 authors Giuseppe Giaccone
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2010 (First Publication: 20 July 2010)
  • The goal of this study was to characterize and classify pulmonary neuroendocrine tumors based on array comparative genomic hybridization (aCGH). Using aCGH, we performed karyotype analysis of 33Continue Reading
  • I-Shou Chang, Shih Sheng Jiang, +25 authors Chao A. Hsiung
  • Medicine
  • American journal of respiratory and critical care…
  • 2017 (First Publication: 1 March 2017)
  • Rationale: Patients with non‐small cell lung cancer (NSCLC) with mutated epidermal growth factor receptor (EGFR) are relatively sensitive to EGFR‐tyrosine kinase inhibitor (TKI) treatment and haveContinue Reading
  • Meng-Tzu Weng, Junsu Lee, +16 authors Ji Luo
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2012 (First Publication: 26 December 2012)
  • Cancers with Ras mutations represent a major therapeutic problem. Recent RNAi screens have uncovered multiple nononcogene addiction pathways that are necessary for the survival of Ras mutant cells.Continue Reading
  • Jinqiu Chen, Junsu Lee, +5 authors Giuseppe Giaccone
  • Biology, Medicine
  • Molecular cancer therapeutics
  • 2013 (First Publication: 1 November 2013)
  • Developing proteomic biomarkers is valuable for evaluating therapeutic effects of drugs and generating better treatment strategies. However, conventional protein analysis is often challenging due toContinue Reading
  • Jinqiu Chen, Junsu Lee, +5 authors Giuseppe Giaccone
  • Medicine
  • 2013 (First Publication: 15 April 2013)
  • Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Molecular targeted therapy is widely used to treat non-small cell lung cancer (NSCLC) and genomic analysis has beenContinue Reading