Junko Sunaga

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Risk factors for acquiring hepatitis E among individuals in industrialized countries including Japan are not fully understood. We investigated whether Japanese blood donors with or without an elevated alanine aminotransferase (ALT) level are likely to have hepatitis E virus (HEV) infection. Serum samples were collected from 5,343 voluntary blood donors(More)
Coupling interactions among mechanical and biochemical factors are important for the realization of various cellular processes that determine cell migration. Although F-actin network dynamics has been the focus of many studies, it is not yet clear how mechanical forces generated by actomyosin contractility spatiotemporally regulate this fundamental aspect(More)
The human finger is said to be the extension of the brain and can convey the information on mechanical, thermal, and tissue damaging. The quantitative prediction of blood flow rate and heat generation are of great importance for diagnosing blood circulation illness and for the noninvasive measurement of blood glucose. In this study, we developed a coupled(More)
Hepatitis E is rare in Japan but is occurring more frequently than previously thought. To investigate whether de novo subclinical infection of hepatitis E virus (HEV) has recently increased in Japan, HEV RNA was assayed in serum samples obtained from 4019 Japanese voluntary blood donors with alanine aminotransferase (ALT) of ≥61 IU/l, who are likely to have(More)
Condensation/aggregation process of rabbit-derived chondrocytes on a fibroin-coated patterned substrate was observed to estimate initial aggregation process in fibroin sponge. Chondrocytes were seeded on array of 160 microm diameter pits in three densities: 5 cells/pit (2.5 x 10(4) cells/cm(2), LOW), 15 cells/pit (7.5 x 10(4) cells/cm(2), MID) and 25(More)
The human finger is said to be the extension of the brain and can convey the information on mechanical, thermal, and tissue damaging. The quantitative prediction of blood flow rate and thermal generation are of great importance for diagnosing blood circulation illness and for the noninvasive measurement of blood glucose. In this study, we developed a(More)
Osteocytes form a three-dimensional (3D) cellular network within the mineralized bone matrix. The cellular network has important roles in mechanosensation and mechanotransduction related to bone homeostasis. We visualized the embedded osteocyte network in chick calvariae and observed the flow-induced Ca2+ signaling in osteocytes using 3D time-lapse imaging.(More)
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