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This study was performed to identify plasma microRNAs (miRNAs) as diagnostic biomarkers for pancreatic cancer (PCa) and to assess their supplementary role with serum CA19-9 in early identification of tumors. Plasma RNAs were extracted from 140 PCa patients, 111 chronic pancreatitis (CP) patients and 68 normal controls, and the relative abundances of seven(More)
OBJECTIVES Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) is a useful tool in the diagnosis of pancreatic masses. Genetic analysis of these samples could increase the sensitivity and specificity of diagnosis. This study aimed to evaluate the usefulness of a novel method for the detection of mutations in the KRAS (Kirsten rat sarcoma-2(More)
For a computing system to be trusted, it is equally important to verify that the system performs no more and no less functionalities than desired. Traditional testing and verification methods are developed to validate whether the system meets all the requirements. They cannot detect the existence or show the non-existence of the unknown undesired(More)
Peak current is one of the important considerations for circuit design and testing in the deep sub-micron technology. In a synchronous finite state machine (FSM), it is observed that the peak current happens at the moment of state transitions and it has a strong correlation with the maximum number of state registers switching in the same direction(More)
Energy efficiency has become an important concern for the design of communication systems, particularly the wireless sensor networks where recharging battery might not be feasible. In this paper, we investigate how error correction coding (ECC) and transmission power level can impact the packet loss rate and transmission energy. We focus our analysis on the(More)
In this paper, we describe the formatting guidelines for ACM SIG Proceedings. Traditionally silence in VoIP applications is detected by a VAD algorithm after G.729 compression, both have high computational and energy cost. However, such cost on silence frames will be completely wasted because the detected silence frames will not be sent to receiver. We(More)
Dual-Vt technology is effective in leakage reduction and has been implemented in industry EDA tools. However, on-chip temperature is regarded as uniformly distributed over the chip, with a pre-assumed value. This assumption does not hold for designs in the deep sub-micron deomain as on-chip temperature variation becomes more and more significant. As a(More)
Process-induced mechanical stress is used to enhance carrier mobility and drive current in contemporary CMOS technologies. Stressed cells have reduced delay but larger leakage consumption. Its efficient power/delay trading ratio makes mechanical stress an enticing alternative to other power optimization techniques. This paper proposes an effective(More)