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Circulating Microparticles, Blood Cells, and Endothelium Induce Procoagulant Activity in Sepsis Through Phosphatidylserine Exposure
ABSTRACT Sepsis is invariably accompanied by altered coagulation cascade; however, the precise role of phosphatidylserine (PS) in inflammation-associated coagulopathy in sepsis has not been wellExpand
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Phosphatidylserine exposing-platelets and microparticles promote procoagulant activity in colon cancer patients
BackgroundColon cancer is invariably accompanied by altered coagulation activity; however, the precise role of phosphatidylserine (PS) in the hypercoagulable state of colon cancer patients remainsExpand
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Phosphotidylserine exposure and neutrophil extracellular traps enhance procoagulant activity in patients with inflammatory bowel disease.
  • Z. He, Y. Si, +17 authors J. Shi
  • Medicine
  • Thrombosis and haemostasis
  • 10 December 2015
Inflammatory bowel disease (IBD)-associated thromboembolic event often lacks precise aetiology. The aim of this study was to investigate the contribution of phosphatidylserine (PS) exposure andExpand
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Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release
The mechanisms contributing to an increased risk of thrombosis in uremia are complex and require clarification. There is scant morphological evidence of membrane-dependent binding of factor Xa (FXa)Expand
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Enhanced procoagulant activity of platelets after chemotherapy in non-small cell lung cancer
ABSTRACT The procoagulant status of patients with non-small cell lung cancer (NSCLC) after chemotherapy is poorly characterized and the role of platelets in hypercoagulative state of NSCLC isExpand
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Phosphatidylserine on blood cells and endothelial cells contributes to the hypercoagulable state in cirrhosis
The mechanism of thrombogenicity in cirrhosis is largely unknown. Our objective was to study the relationship between phosphatidylserine on blood cells and endothelial cells and the hypercoagulableExpand
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Enhanced Procoagulant Activity on Blood Cells after Acute Ischemic Stroke
The role of phosphatidylserine (PS)-mediated procoagulant activity (PCA) in stroke remains unclear. To ascertain this role, early dynamic evolution of PS exposure on blood cells and releasedExpand
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Phosphatidylserine on microparticles and associated cells contributes to the hypercoagulable state in diabetic kidney disease
  • M. Yu, R. Xie, +10 authors J. Shi
  • Medicine
  • Nephrology, dialysis, transplantation : official…
  • 1 December 2018
Background Relatively little is known about the role of phosphatidylserine (PS) in procoagulant activity (PCA) in patients with diabetic kidney disease (DKD). This study was designed to evaluateExpand
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Contributions of phosphatidylserine-positive platelets and leukocytes and microparticles to hypercoagulable state in gastric cancer patients
Hypercoagulability in gastric cancer is a common complication and a major contributor to poor prognosis. This study aimed to determine procoagulant activity of blood cells and microparticles (MPs) inExpand
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Dissimilarity of increased phosphatidylserine-positive microparticles and associated coagulation activation in acute coronary syndromes
ObjectiveWe evaluated cellular origin, numbers, and procoagulant activity of phosphatidylserine-positive microparticles (MPs) among subgroups in acute coronary syndromes (ACS). Materials andExpand
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