Junichi Hashimoto

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Monte-Carlo Tree Search (MCTS) is a very successful approach for improving the performance of game-playing programs. This paper presents the Accelerated UCT algorithm, which overcomes a weakness of MCTS caused by deceptive structures which often appear in game tree search. It consists in using a new backup operator that assigns higher weights to recently(More)
BACKGROUND Sunitinib is an oral multitargeted tyrosine kinase inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptors, as well as of other receptor types. We have performed a feasibility study to investigate the safety of sunitinib in combination with pemetrexed for treatment of advanced refractory solid tumors. (More)
BACKGROUND Platelet-rich plasma (PRP) can provide an assortment of growth factors, but how PRP effects bone regeneration is still unknown. The aim of the study was to explore an optimal method of using PRP and bone marrow stromal cells (BMSCs). METHODS An in vitro experiment was first conducted to determine an appropriate quantity of PRP. BMSCs were(More)
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