Junhong Min

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Super resolution microscopy such as STORM and (F)PALM is now a well known method for biological studies at the nanometer scale. However, conventional imaging schemes based on sparse activation of photo-switchable fluorescent probes have inherently slow temporal resolution which is a serious limitation when investigating live-cell dynamics. Here, we present(More)
The quality of super-resolution images obtained by single-molecule localization microscopy (SMLM) depends largely on the software used to detect and accurately localize point sources. In this work, we focus on the computational aspects of super-resolution microscopy and present a comprehensive evaluation of localization software packages. Our philosophy is(More)
Structured illumination microscopy (SIM) breaks the optical diffraction limit by illuminating a sample with a series of line-patterned light. Recently, in order to alleviate the requirement of precise knowledge of illumination patterns, structured illumination microscopy techniques using speckle patterns have been proposed. However, these methods require(More)
—Localization microscopy such as STORM/PALM achieves the super-resolution by sparsely activating photo-switchable probes. However, to make the activation sparse enough to obtain reconstruction images using conventional algorithms, only small set of probes need to be activated simultaneously, which limits the temporal resolution. Hence, to improve temporal(More)
Super-resolution localization microscopy relies on sparse activation of photo-switchable probes. Such activation, however , introduces limited temporal resolution. High-density imaging overcomes this limitation by allowing several neighboring probes to be activated simultaneously. In this work, we propose an algorithm that incorporates a continuous-domain(More)
Localization microscopy achieves nanoscale spatial resolution by iterative localization of sparsely activated molecules, which generally leads to a long acquisition time. By implementing advanced algorithms to treat overlapping point spread functions (PSFs), imaging of densely activated molecules can improve the limited temporal resolution, as has been well(More)
During the pre-purchase stage, consumers look for information in the external environment to verify marketers' claims, and by doing so, they are likely to encounter some reliable independent information such as consumer reports or technical reports. Using a Discrete Choice Experiment, this chapter shows that consumers use marketers' claims as reference(More)
Purpose: Due to the potential risk of inducing cancers, radiation dose of X-ray CT should be reduced for routine patient scanning. However, in low-dose X-ray CT, severe artifacts usually occur due to photon starvation, beamhardening, etc, which decrease the reliability of diagnosis. Thus, high quality reconstruction from low-dose X-ray CT data has become(More)
Higher education has never truly recognized the importance of garnering the resources of alumni by expending university efforts in developing, controlling, and maintaining relationships with alumni. The purpose of this research is to tackle the long-term relationship marketing question. Drawing on the social marketing and relationship marketing literature,(More)