Jung-hyun Cho

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Although asbestos causes malignant pleural mesothelioma (MPM), rising from lung mesothelium, the molecular mechanism has not been suggested until now. Extremely low mutation rate in classical tumor suppressor genes (such as p53 and pRb) and oncogenes (including Ras or myc) indicates that there would be MPM-specific carcinogenesis pathway. To address this,(More)
BACKGROUND The etiology of cervical heterotopic pregnancy is unknown, but most are associated with assisted reproductive techniques. Various types of conservative management to save the intrauterine pregnancy have been attempted. CASE A 35-year-old woman conceived after in vitro fertilization/embryo transfer for primary malefactor infertility. At 7(3/7)(More)
Cytocompatible, co-doped cerium oxide nanoparticles exhibited strong upconversion properties that were found to kill lung cancer cells by inducing apoptosis thereby demonstrating the potential to be used as clinical contrast agents for imaging and as therapeutic agents for treatment of cancer.
BACKGROUND Recent data suggest that cigarette smoking (CS) might decrease the risk of cardiovascular events in patients with ST-segment-elevation myocardial infarction (STEMI) or established cardiovascular disease. Although it may be related to the effect of CS on the metabolism of clopidogrel, the association between the extent of CS and(More)
BACKGROUND AND OBJECTIVES Smoking increases inhibition of clopidogrel-induced platelet reactivity in patients undergoing elective coronary stenting. However, an association between pre-admission smoking (PS) and post-clopidogrel platelet reactivity in patients with acute myocardial infarction (AMI) has not been determined. SUBJECTS AND METHODS Study(More)
Toll-like receptors (TLRs), which are mainly expressed in antigen presenting cells, perform a critical role in innate immunity by recognizing the specific structural patterns of pathogens and transducing signals to induce an inflammatory reaction. Although it has been reported that various solid cancers express endosomal TLRs, TLR3, 7, 8, and 9, the(More)
The transosseous-equivalent (TOE) repair of the rotator cuff tears was invented to make up for several shortcomings of the double-row (DR) repair. However, no studies have compared the clinical aspects of the DR repair and the TOE technique, supporting the superior results of the TOE technique over the DR repair, including the benefit of minimizing surgical(More)
An application portal has been developed to support the execution of a computational fluid dynamics (CFD) numerical model that simulates hydrodynamic flow instability of the coaxial injector in the liquid rocket engine. The CFD application has been integrated into a web-based portal framework so that users can utilize resources available in grid computing(More)
Stress has been suggested as one of important cause of human cancer without molecular biological evidence. Thus, we test the effect of stress-related hormones on cell viability and mitotic fidelity. Similarly to estrogen, stress hormone cortisol and its relative cortisone increase microtubule organizing center (MTOC) number through elevated expression of(More)