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The p14(ARF)-MDM2-p53 pathway constitutes an effective mechanism for protecting cells from oncogenic stimuli such as activated Ras and Myc. Importantly, Ras activation induces p14(ARF) and often occurs earlier than p53 inactivation during cancer development. Here, we show that RUNX3, a tumor suppressor in various tumors including stomach, bladder, colon,(More)
This paper investigates the effectiveness of measures related to vocal tract characteristics in classifying normal and pathological speech. Unlike conventional approaches that mainly focus on features related to the vocal source, vocal tract characteristics are examined to determine if interaction effects between vocal folds and the vocal tract can be used(More)
According to time sensitive traffic service are increased, a necessity of technology that guarantees low delay among digital devices in the LAN is increased. Institute of Electrical and Electronics Engineers(IEEE) 802.1 Audio/Video Bridging Task Group(AVB TG) is carrying out research on time synchronization and guarantee of low delay among digital devices(More)
—Efficient service description and modeling methodologies are essential for dynamic service composition to provide autonomous services for users in ubiquitous computing environments. In our previous research, we proposed a 'u-service' ontology which is an abstract and structured concept for device operations in ubiquitous environments. One of the problems(More)
This paper proposes a new feature extraction method for automatically detecting pathological voice in a normal conversation scenario. Unlike conventional approaches that utilize the static harmonic-to-noise ratio (HNR) characteristics of sustained vowel, the proposed method considers the dynamic movements of articulatory organs depending on the types of(More)
To provide dynamic services for users in a ubiquitous environment, an efficient context-aware service discovery mechanism is essential. Most of current researches are focused on composing services which satisfy pre-defined service specifications, by checking the availability of the devices and finding services that satisfy the user's preference. In this(More)
To determine the change in pesticides used during suicide attempts after the 2012 paraquat (PQ) ban, we evaluated the annual number of suicide attempts by pesticide ingestion between 2011 and 2014. We extracted demographic, clinical outcome, and pesticide class data from the medical records of 1,331 patients that attempted suicide by pesticide ingestion.(More)