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Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs.
- Byung-Hak Kim, C. Won, +8 authors Myounghwan Kim
- Biology, Medicine
- Biochemical pharmacology
- 1 October 2013
Aberrantly activated signal transducer and activator of transcription (STAT) proteins are implicated with human cancers and represent essential roles for cancer cell survival and proliferation.… Expand
Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display.
- Hai-yan Hong, Jung Sook Choi, +8 authors Byungheon Lee
- Journal of controlled release : official journal…
- 12 November 2008
Focal cerebral ischemia, known as stroke, is caused by a sudden interruption in the blood supply to the brain. We attempted to identify peptides that can home to ischemic stroke tissue and detect the… Expand
Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model
- Jung Sook Choi, Jaechan Park, K. Suk, C. Moon, Yong-Ki Park, H. Han
- Stroke research and treatment
- 16 March 2011
Intercellular adhesion molecule-1 (ICAM-1) in cerebral vascular endothelium induced by ischemic insult triggers leukocyte infiltration and inflammatory reaction. We investigated the mechanism of… Expand
Protective effect of Triticum aestivum L. extract and its component, starch, in rat focal cerebral ischemia
A Comparative Study on the Postpartum Depression of Vietnamese Marriage Immigrant Women and Korean Women
Purpose: This study aimed to examine postpartum depression of Vietnamese married immigrant women and Korean women, and to identify factors that affect postpartum depression. Methods: Subjects of one… Expand
Assessment of Energy Intake and Physical Activity Level for Korean Farmers to Establish Estimated Energy Requirements during the Off-Season for Farmers
The purpose of this study was to assess the physical activity level of Korean farmers to establish estimated energy requirements during the off-season. Subjects were 90 healthy males (n = 25) and… Expand
Relative Antioxidant Activities of Quercetin and Its Structurally Related Substances and Their Effects on NF-κB/CRE/AP-1 Signaling in Murine Macrophages
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by the oxidative burst in activated macrophages and neutrophils cause oxidative stressimplicated diseases. Quercetin is… Expand
Immunomodulatory Activities of the Benzoxathiole Derivative BOT-4-One Ameliorate Pathogenic Skin Inflammation in Mice.
T cell-mediated immune responses play an important role in body protection. However, aberrantly activated immune responses are responsible for inflammatory and autoimmune diseases. The regulation of… Expand
Water extract of Triticum aestivum L. and its components demonstrate protective effect in a model of vascular dementia.
Although vascular dementia is the second leading cause of dementia and often underdiagnosed, there are no drugs yet approved for the treatment of vascular dementia. In this study, it is demonstrated… Expand
Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling
Persistently activated JAK/STAT3 signaling pathway plays a pivotal role in various human cancers including major carcinomas and hematologic tumors, and is implicated in cancer cell survival and… Expand