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Hypoxia-inducible factor-1 (HIF-1) is a transcription factor involved in the cancer cell adaptation to hypoxia, a leading cause of tumor malignancy. Thus, control of HIF-1alpha expression may assist in treatment of cancer. The expression of HIF-1alpha is finely regulated via alterations in not only HIF-1alpha protein stability but also mRNA stability.(More)
In this study, the coefficient of thermal expansion (CTE) and the elastic modulus of epoxy molding compound (EMC) are measured using fabricated specimens and then the measured values are compared with the predicted values by theoretical equations (such as dilute suspension method, self consistent method, Hashin-Shtrikman's bounds, Shapery's bounds and(More)
Edwards syndrome, also called trisomy 18, is one of the most common autosomal anomalies. The survival rate of patients with Edwards syndrome is very low and its characteristic findings include cardiac malformations, mental retardation, growth retardation, specific craniofacial anomalies, clenched hands, rocker-bottom feet, and omphalocele. Compared with the(More)
BACKGROUND & AIMS Acquisition of resistance to the antiproliferative effect of transforming growth factor (TGF)-beta1 is crucial for the malignant progression of cancers. In this study, we sought to determine whether deregulated expression of tristetrapolin (TTP), a negative posttranscriptional regulator of c-Myc, confers resistance to the antiproliferative(More)
OBJECTIVE To identify surgical prognostic factors and to characterize clinical features according to the location of the intracranial ictal onset zone of frontal lobe epilepsy (FLE) in order to assess the role of various diagnostic modalities, including concordances with presurgical evaluations. METHODS We studied 71 FLE patients who underwent epilepsy(More)
The acculturation effect of immigrant women on birth outcomes varies by race. We examined birth outcomes of three groups of births for the period 1995-2004, USA births to the USA-born Korean mothers, USA births to the non-USA-born Korean mothers, and births in Korea. In singleton USA births to both Korean parents, average birth weight was 3,294 g for the(More)
Epidermoid cysts are benign developmental anomalies that are rarely observed in the oral cavity of neonate. If large in size, especially in the developing fetus or newborn infant, they can cause swallowing difficulty and occasionally respiratory difficulty. We report a case of epidermoid cyst in the oral cavity detected prenatal sonography. The sonographic(More)
Large deformation of thin silicon wafer on flat plate induced by film stress was analyzed by analytic method and finite element analysis (FEA) method considering bifurcation and gravitation. Bifurcation criterion was obtained by energy method, and resulting warpage was calculated from obtained curvature. Anisotropy of substrate and film material was(More)
Explicit analytic solutions of the deflection of the overhang during the wirebonding process were derived. The wirebonding on overhang were modeled as a cantilever plate subjected to concentrated force at the corner or edge. Depending on the length of the overhang and the position of the bonding pad, the cantilever plate was divided into three types. The(More)
This paper describes a fiber optic sensor suitable for noncontact detection of ultrasonic waves. This sensor is based on the fiber optic Sagnac interferometer, which has a path-matched configuration and does not require active stabilization. Quadrature phase bias between two interfering laser beams in the Sagnac loop is applied by controlling the(More)