Jung Bae Song

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A protein-cleaving catalyst specific for a disease-related protein can be used as a catalytic drug. As the first protein-cleaving catalyst selective for a protein substrate, a catalyst for myoglobin was designed by attaching Cu(II) or Co(III) complex of cyclen to a binding site searched by a combinatorial method using peptide nucleic acid monomers as(More)
Previously, we reported the first substrate-selective artificial protease by using myoglobin as the substrate. Target-selective peptide-cleaving catalysts can be used as drugs if the target is a protein or an oligopeptide related to a disease. For example, a peptide-cleaving catalyst specifically recognizing HIV protease and rapidly cleaving it into two(More)
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