June A Takahashi

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We report a case of a bright, alert patient with central neurogenic hyperventilation (CNH) associated with cerebral malignant lymphoma. CNH is a syndrome comprising normal or elevated arterial oxygen tension, decreased arterial carbon dioxide tension, and respiratory alkalosis in the absence of cardiac or pulmonary disease that stimulates a compensatory(More)
Background. Anterior clinoidectomy is useful in the surgical treatment of paraclinoid and parasellar lesions. Previously reported procedures require expertise in drilling, the alternative method reported here reduces the drilling procedure. Methods and results. En-bloc clinoidectomy is performed intradurally via the standard pterional approach. A 1 to 2(More)
Important pathologic features of cerebral metastases include the route of spread of tumor cells to the brain, differences among metastases based on location in dura mater, leptomeninges, and brain parenchyma, differences based on primary tumor site, both known and unknown, the means of spread of metastases within the brain, and the brain's reactions to(More)
Histopathological classification of gliomas is often clinically inadequate due to the diversity of tumors that fall within the same class. The goal of the present study was to identify prognostic molecular features in diffusely infiltrating gliomas using gene expression profiling. We selected 3456 genes expressed in gliomas, including 3012 genes found in a(More)
Objectives and importance. It is important to evaluate the seizure manifestation of epilepsy before surgical planning. A patient with partial epilepsy manifesting hypersalivation who underwent resection of the epileptogenic foci with satisfactory postoperative seizure control is reported. Clinical presentation and intervention. A 26-year-old man, with a(More)
Background. Intrinsic midbrain glioma has been one of the most challenging therapeutic tasks in neurosurgery due to its prognosis and risks associated with surgical procedures. It is known that the prognosis of pilocytic astrocytoma is relatively good if radical resection can be achieved without severe complications. In order to remove pilocytic astrocytoma(More)
Mesenchymal chondrosarcoma, ®rst described by Lichtenstein and Bernstein as a distinct entity in 1959 [3], is an aggressive variant of chondrosarcoma de®ned by the coexistence of nests of well-de®ned cartilaginous tissue within a proliferation of primitive mesenchymal cells [4]. Mesenchymal chondrosarcoma is characteristic because of its strong tendency for(More)
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