A step is taken towards fusing symbolic and decision-theoretic problem solving in a cognitive architecture by implementing the latter in an architecture within which the former has already been demonstrated. The graphical models upon which the architecture is based enable a uniform implementation of both varieties of problem solving. They also enable a… (More)
This paper presents a method for designing a reusable software controller architecture. The proposed controller architecture is designed for a specific domain of controllers (e.g. zero order, first order, second order ..... nth), and it can be reused to develop a specific controller within this specific domain. The basic idea of this reusable controller… (More)
Sterile inflammatory insults, such as ischemia-reperfusion (I/R) injury, result from pathogenic factors, including damage-associated molecular pattern signaling, activation of innate immunity, and upregulation of proinflammatory cytokines. At the same time, a number of protective, or prosurvival, pathways are also activated, and the extent of end-organ… (More)
UNLABELLED Lamin B1 is a component of the nuclear lamina and plays a critical role in maintaining nuclear architecture, regulating gene expression and modulating chromatin positioning. We have previously shown that LMNB1 gene duplications cause autosomal dominant leukodystrophy (ADLD), a fatal adult onset demyelinating disease. The mechanisms by which… (More)
Electromagnetic absorption and subsequent heating of nanoparticle solutions and simple NaCl ionic solutions is examined for biomedical applications in the radiofrequency range at 13.56 MHz. It is shown via both theory and experiment that for in vitro measurements the shape of the solution container plays a major role in absorption and heating.