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OBJECTIVE To investigate the role of CD4+CD25+Foxp3+ regulatory T cells (Treg) in type 2 diabetic nephropathy and provide new clues for prevention and treatment of type 2 diabetic nephropathy. METHODS Flow cytometry was used to analyze the expression rate of CD4+CD25+Foxp3+ Treg cells in 60 patients with type 2 diabetes and 15 normal subjects. RESULTS(More)
AIM To investigate the possible mechanisms of ginsenoside Rg1 promoting bone marrow stromal cell (BMSC) proliferation. METHODS BMSC were isolated from bone marrow of Sprague-Dawley rats and maintained in vitro. After stimulation with 1 micromol/L ginsenoside Rg1 for the indicated time, the proliferation ability of BMSC were assessed by(More)
The objective of this study was to investigate correlations between oxidative stress, metabolism of mineral elements, and lameness in dairy cows. Forty multiparous Chinese Holstein dairy cows were selected and divided into two groups (healthy vs lame, n = 20) by gait score. The experiment lasted for 60 days and samples of hair, blood, and hoof were(More)
BACKGROUND Platelet-monocyte aggregates (PMA) and C-reactive protein (CRP) are increased in unstable coronary disease. The interrelation of PMA with platelet activation, systemic inflammation, and their association with markers of myocardial injury has not been studied extensively. HYPOTHESIS The study was undertaken to evaluate the association of CRP,(More)
OBJECTIVE To measure the neutralization activity in vitro of the antibodies induced by recombinant TGFbeta1 vaccine and to evaluate the vaccine's anti-liver fibrosis activity. METHODS Balb/c mice were immunized with a fusion protein of the human TGFbeta1 epitope-inserted into a hepatitis B core antigen using a prokaryotic expression system. The antibody(More)
The problem of delay-dependent robust stability and stabilization for a class of uncertain nonlinear systems with time-varying delay, is studied. The parameter uncertainty under consideration is norm bounded and possibly time-varying. The time delay considered here is assumed to be size-bounded but otherwise arbitrarily fast time-varying. Based on a special(More)
BACKGROUND Previous studies have reported that natriuretic peptides in the blood and pleural fluid (PF) are effective diagnostic markers for heart failure (HF). These natriuretic peptides include N-terminal pro-brain natriuretic peptide (NT-proBNP), brain natriuretic peptide (BNP), and midregion pro-atrial natriuretic peptide (MR-proANP). This systematic(More)
To evaluate the effects of chelated Zn/Cu/Mn on redox status, immune responses and hoof health in lactating Holstein cows, 48 head in early lactation were divided into healthy or lame groups according to their gait score. Cows were fed the same amount of Zn/Cu/Mn as sulfate salts or in chelated forms for 180 days, and foot-and-mouth disease (FMD) vaccine(More)
This paper is concerned with robust H ∞ control for uncertain stochastic time-delay systems with norm-bounded parametric uncertainties. Based on an integral inequality and slack matrix technique, delay-dependent bounded real lemma (BRL) and the condition for the existence of robust H ∞ controller are presented. For all the admissible parametric(More)
BACKGROUND Eppin (epididymis protease inhibitor) appears to play an important role in primate fertility. However, the function of Eppin and its antibody in men and its relationship with men's infertility are poorly studied. To reveal the significance and possibility of detection of anti-Eppin antibody in clinical infertilty cases, we developed an(More)