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- Publications
- Influence
Human Cytomegalovirus Directly Induces the Antiviral Protein Viperin to Enhance Infectivity
- Jun-Young Seo, R. Yaneva, E. Hinson, P. Cresswell
- Biology, Medicine
- Science
- 27 May 2011
Human cytomegalovirus uses a host-encoded antiviral protein to its own advantage. Viperin is an interferon-inducible protein that is directly induced in cells by human cytomegalovirus (HCMV)… Expand
Viperin: a multifunctional, interferon-inducible protein that regulates virus replication.
- Jun-Young Seo, R. Yaneva, P. Cresswell
- Biology, Medicine
- Cell host & microbe
- 15 December 2011
Viperin is an interferon-inducible protein that inhibits the replication of a variety of viruses by apparently diverse mechanisms. In some circumstances, it also plays a role in intracellular… Expand
Sequence Requirements for Localization of Human Cytomegalovirus Tegument Protein pp28 to the Virus Assembly Compartment and for Assembly of Infectious Virus
- Jun-Young Seo, W. Britt
- Biology, Medicine
- Journal of Virology
- 1 June 2006
ABSTRACT The human cytomegalovirus UL99 open reading frame encodes a 190-amino-acid (aa) tegument protein, pp28, that is myristoylated and phosphorylated. pp28 is essential for assembly of infectious… Expand
Rapid Genetic Engineering of Human Cytomegalovirus by Using a Lambda Phage Linear Recombination System: Demonstration that pp28 (UL99) Is Essential for Production of Infectious Virus
- W. Britt, M. Jarvis, Jun-Young Seo, Derek D. Drummond, J. Nelson
- Biology, Medicine
- Journal of Virology
- 1 January 2004
ABSTRACT A highly efficient lambda phage recombination system previously utilized for studies of bacterial artificial chromosome (BAC)-maintained mouse chromosomal DNA was adapted for the study of… Expand
Viperin Regulates Cellular Lipid Metabolism during Human Cytomegalovirus Infection
- Jun-Young Seo, P. Cresswell
- Biology, Medicine
- PLoS pathogens
- 1 August 2013
Human cytomegalovirus (HCMV) has been shown to induce increased lipogenesis in infected cells, and this is believed to be required for proper virion envelopment. We show here that this increase is a… Expand
Cytoplasmic Envelopment of Human Cytomegalovirus Requires the Postlocalization Function of Tegument Protein pp28 within the Assembly Compartment
- Jun-Young Seo, W. Britt
- Biology, Medicine
- Journal of Virology
- 28 March 2007
ABSTRACT The assembly of herpesvirus remains incompletely defined due to the structural complexity of these viruses. Although the assembly of the capsid of these large DNA viruses is well studied and… Expand
Multimerization of Tegument Protein pp28 within the Assembly Compartment Is Required for Cytoplasmic Envelopment of Human Cytomegalovirus
- Jun-Young Seo, W. Britt
- Biology, Medicine
- Journal of Virology
- 2 April 2008
ABSTRACT Human cytomegalovirus (HCMV) UL99-encoded pp28 is an essential tegument protein required for envelopment and production of infectious virus. Nonenveloped virions accumulate in the cytoplasm… Expand
HCMV-encoded US7 and US8 act as antagonists of innate immunity by distinctively targeting TLR-signaling pathways
- Areum Park, Eun A. Ra, +6 authors B. Park
- Biology, Medicine
- Nature Communications
- 11 October 2019
The mechanisms by which many human cytomegalovirus (HCMV)-encoded proteins help the virus to evade immune surveillance remain poorly understood. In particular, it is unknown whether HCMV proteins… Expand
and for Assembly of Infectious Virus pp 28 to the Virus Assembly Compartment Human Cytomegalovirus Tegument Protein Sequence Requirements for Localization of
- Jun-Young Seo, W. Britt
- 2006
- 1
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재활용가능한 친환경 전력용케이블 절연재료의 전기적 특성 비교
- 이준호, 김성중, 권기형, 김철호, Jun-Young Seo, Kyunghoon Jang
- Engineering
- 1 May 2012