Jun Uchida

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BACKGROUND Thymidylate synthase (TS), a key enzyme in the de novo synthesis of thymidine, is an important chemotherapeutic target for malignant tumours including lung cancer. Although inhibition of TS has an antiproliferative effect in cancer cells, the precise mechanism of this effect has remained unclear. METHODS We examined the effects of TS inhibition(More)
Performing general human behavior by experts' navigation is expected to be realized as wearable and ubiquitous technologies and computing develop. For simple, ordinary behavior, a person does not need the assistance of an expert. However, if one is standing next to an injured/ill person, one needs the instruction on performing first aid treatment from an(More)
In recent years, a new stick-type odor identification test, the odor-stick identification test for Japanese (OSIT-J) has been developed in Japan. Thirteen odors familiar to Japanese people are used in this test. The OSIT-J is an olfactory discrimination test and is significantly correlated with the average recognition threshold of T & T olfactometry, which(More)
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