Jun Miyazaki

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The aim of this study was to investigate how insulin secretion is controlled by phosphorylation of the myosin light chain (MLC). Ca2+-evoked insulin release from pancreatic islets permeabilized with streptolysin O was inhibited by different monoclonal antibodies against myosin light-chain kinase (MLCK) to an extent parallel to their inhibition of purified(More)
BACKGROUND & AIMS Pancreatic polypeptide (PP) is a 36-amino acid hormone produced by F cells within the pancreatic islets and the exocrine pancreas. The definitive function of PP in mammalian physiology remains to be determined. This study examined the effects of chronic overexpression of PP through the development of PP transgenic mice. METHODS PP(More)
The purpose of this study is to propose Context-Aware Support Vector Machine (C-SVM) for application in a context-dependent recommendation system. It is important to consider users’ contexts in information recommendation as users’ preference change with context. However, currently there are few methods which take into account users’ contexts(More)
OBJECTIVE We aimed to elucidate risk factors for intravesical recurrence of high-grade T1 bladder cancer in the second transurethral resection era. METHODS The analysis included 73 patients with high-grade T1 bladder cancer on initial transurethral resection. The median follow-up period was 49.2 months. Recurrence-free survival, progression-free survival(More)
This paper proposes a recommendation method considering users' time series contexts which are situations that have occurred / will occur in the past/future. There are some recommendation methods that provide information suitable for users' action patterns as the recommendation methods considering them. These methods provide information referring to the(More)
To determine virulence-related genes in uropathogenic Escherichia coli (UPEC) showing invasiveness to T-24 bladder cancer cells, genomic subtractive hybridization was performed between a highly invasive and a less invasive strain. Forty-nine DNA fragments were isolated from the invasive strain. One of them showed homology with Salmonella invA gene. By(More)
In this paper, we present a tag-based collaborative filtering recommendation method for use with recently popular online social tagging systems. Combining the information provided by tagging systems with the effective recommendation abilities given by collaborative filtering, we provide a website recommendation system which provides relevant, credible(More)
We propose an efficient distributed query processing method for large XML data by partitioning and distributing XML data to multiple computation nodes. There are several steps involved in this method; however, we focused particularly on XML data partitioning and dynamic relocation of partitioned XML data in our research. Since the efficiency of query(More)
At FXPAL Japan we have built an (experimental) Smart Conference Room (SCR) that contains multiple cameras, microphones, displays, and capture devices. Based on our experience, in this paper we discuss research and open issues in constructing SCRs like the one built at FXPAL for the purpose of automatic content analysis. Our discussion is grounded on a novel(More)