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Energy efficient and reliable data forwarding becomes important if resources are limited such as in Wireless Sensor Networks. Although Directed Diffusion, a data centric routing approach is widely used in Wireless Sensor Networks,it is inefficient in terms of reliability and energy efficiency. In this paper we present a new routing scheme for Wireless(More)
Transforming growth factor-β (TGF-β) is a potent anti-inflammatory cytokine that regulates interleukin-1 receptor and Toll-like receptor (TLR) signalling. Here we show a novel mechanism where TGF-β1-induced K48-linked polyubiquitination and degradation of the adaptor MyD88 protein is dependent on the Smad6 protein, but not Smad7, and mediated by recruitment(More)
Transforming growth factor-beta (TGF-beta) is a cytokine important in inducing epithelial-mesenchymal transition (EMT), a crucial morphological event in a wide range of physiological and pathological cellular processes. In this study, we demonstrate that TGF-beta1 induces the EMT phenotype through decreasing the expression of the glutaredoxin 1 (Grx1) gene,(More)
Transforming growth factor-beta1 (TGF-beta1) performs diverse cellular functions, including anti-inflammatory activity. The inhibitory Smad (I-Smad) Smad6 was previously shown to play an important role in TGF-beta1-induced negative regulation of Interleukin-1/Toll-like receptor (IL-1R/TLR) signaling through binding to Pellino-1, an adaptor protein of(More)
We analyzed insulin-like growth factor receptor I (IGF-IR) and insulin growth factor binding protein-3 (IGFBP-3) expression with respect to overall survival and relapse-free survival (RFS) in 460 patients with primary invasive breast cancer using immunohistochemistry. IGF-IR expression had a significant positive correlation with positive estrogen receptor(More)
3D registration is a computer vision technique of aligning multi-view range images with respect to a reference coordinate system. Aligning range images is an important but time-consuming task for complete 3D reconstruction. In this paper, we propose a real-time 3D registration technique by employing the computing power of graphic processing unit (GPU). A(More)
Covalent modifications of the Pellino-1 protein are essential for transmitting innate immune response signals downstream, as the phosphorylation and polyubiquitination of Pellino-1 mediated by the IRAK proteins appear to have roles in regulating Pellino-1 function. In this study, we demonstrate that the Pellino-1 protein is post-translationally modified by(More)
BACKGROUND With increasing awareness for radiation exposure, the study of diagnostic accuracy of coronary CT angiography (CCTA) with low radiation dose techniques is mandatory to both radiologist and clinician. PURPOSE To compare diagnostic performance and effective radiation dose between step-and-shoot prospectively ECG-gated and retrospectively(More)
BACKGROUND/AIMS Mesenchymal tumors are the most frequent submucosal tumors in gastrointestinal trail. We reviewed the mesenchymal tumors which are confirmed by pathology to examine whether the invasive approach of all mesenchymal tumors is necessary. METHODS This study was performed on fifty-nine patients who has mesenchymal tumors confirmed by endoscopic(More)