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The aim of this study was to develop a nonlinear mixed-effects model for the increase in cerebral oximetry (rSO(2)) during the rapid introduction of desflurane, and to determine the effect of hypocapnia and N(2)O on the model. Twelve American Society of Anesthesiologist physical status class 1 and 2 subjects were allocated randomly into an Air and N(2)O(More)
Delirium is a serious complication that commonly occurs in critically ill patients in the intensive care unit (ICU). Delirium is frequently unrecognized or missed despite its high incidence and prevalence, and leads to poor clinical outcomes and an increased cost by increasing morbidity, mortality, and hospital and ICU length of stay. Although its(More)
The rapid introduction of desflurane produces sympathetic stimulation and associated changes, which are represented by increases in blood pressure, heart rate and pupil diameter (1-3). The cerebrovascular response to a rapid increase in desflurane was also reported and considered to be either a coincident or independent change from hemodynamic stimulation(More)
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