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Estimated risk of cardiovascular disease among the HIV-positive patients aged 40 years or older in Taiwan.
TLDR
Higher CVD risk estimates among HIV-positive Taiwanese aged 40-75 were associated with an older age, current smoking, higher systolic blood pressure, hypertriglyceridemia, and hyperglycemia, and smoking cessation could potentially lead to significant decreases of CVDrisk. Expand
Comorbidities among the HIV-Infected Patients Aged 40 Years or Older in Taiwan
TLDR
A significant proportion of the HIV-infected patients aged 50 years or older have multiple comorbidities that may increase the risk for cardiovascular and renal complications and issues of poly-pharmacy among the infected patients who are aging should be addressed. Expand
Trends and outcomes of late initiation of combination antiretroviral therapy driven by late presentation among HIV-positive Taiwanese patients in the era of treatment scale-up
TLDR
While the proportion of late cART initiation decreased over time in Taiwan, late initiation remained in a substantial proportion of HIV-positive patients, and the late initiators had higher risk for poor outcomes. Expand
Effectiveness of a reduced dose of efavirenz plus 2 NRTIs as maintenance antiretroviral therapy with the guidance of therapeutic drug monitoring
TLDR
A therapeutic drug monitoring (TDM)‐guided strategy is used to optimize the EFV dose in HIV‐positive Taiwanese patients to reduce the incidence of adverse effects. Expand
Evolution of hepatitis A virus seroprevalence among HIV-positive adults in Taiwan
TLDR
HAV seroprevalence has decreased with time among HIV- positive adults in Taiwan and the cohort effect has increased the number of young HIV-positive patients that are susceptible to HAV infection in a country without nationwide childhood vaccination program against HAV. Expand
Antiretroviral therapy (ART) management of Low-Level Viremia in Taiwan (ALLEVIATE)
This retrospective study aimed to investigate that if switch of combination antiretroviral therapy (cART) would result in viral suppression (<40 copies/mL) at 48 weeks for patients with persistentExpand
Willingness of human immunodeficiency virus‐positive patients to donate their organs for transplantation in Taiwan: a cross‐sectional questionnaire survey
With the introduction of combination antiretroviral therapy (cART) that has significantly improved survival, human immunodeficiency virus (HIV)‐positive patients may be potential organ donors toExpand
International Congress of Drug Therapy in HIV Infection 23-26 October 2016, Glasgow, UK
TLDR
Two major directions in HIV vaccine development will be discussed: building on the results from RV 144, the clinical trial in Thailand that resulted in the first modest signal of efficacy for a HIV vaccine; and structure‐based immunogen design to elicit broadly neutralizing antibodies. Expand
Incidence and risk factors of herpes zoster in human immunodeficiency virus-positive patients initiating combination antiretroviral therapy in Taiwan.
TLDR
Herpes zoster occurred in 6.5% of HIV-positive Taiwanese patients after initiation of cART, which was associated with prior zoster and baseline CD4 count < 200 cells/μL or baseline PVL > 5 log10 copies/mL. Expand
Presence of Tablet Remnants of Nevirapine Extended-Release in Stools and Its Impact on Virological Outcome in HIV-1-Infected Patients: A Prospective Cohort Study
TLDR
The presence of tablet remnants of NVP XR in stools is not uncommon in HIV-1-infected Taiwanese patients receiving NVPXR-based antiretroviral regimens, which does not have an adverse impact on the virological and immunological outcomes. Expand
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