Julio Urbina

Silvia Orenes Lorente1
Rosario Gómez1
1Silvia Orenes Lorente
1Rosario Gómez
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In this paper we describe the preparation of some biphenylquinuclidine derivatives and their evaluation as inhibitors of squalene synthase in order to explore their potential in the treatment of the parasitic diseases leishmaniasis and Chagas disease. The compounds were screened against recombinant Leishmania major squalene synthase and against Leishmania(More)
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