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There is no precise definition for severe community-acquired pneumonia (SEHP), but there are a number of factors which are associated with a greater severity, and which therefore recommended the admission of these patients in an intensive care unit (ICU). In the present article, we mainly refer to SEHP in the immune competent population. SEHP makes up 8-10%(More)
OBJECTIVES To develop a mathematical model for simulating the daily bed occupancy in an intensive care unit. DESIGN Data collection and retrospective analysis to develop a mathematical model for simulating daily bed occupancy in an intensive care unit. SETTING We studied all admissions to the intensive care unit at the Hospital of Navarra over a 9-yr(More)
OBJECTIVE To study the role of the HLA system in the genetic susceptibility to familial systemic sclerosis (SSc). METHODS HLA class I antigens were determined by classic serological methods and HLA-DRB, -DQA and -DQB genes were analysed by genetic typing in 36 individuals belonging to two families with several individuals affected by SSc. RESULTS The(More)
This paper deals with the management of scarce health care resources. We consider a control problem in which the objective is to minimize the rate of patient rejection due to service saturation. The scope of decisions is limited, in terms both of the amount of resources to be used, which are supposed to be fixed, and of the patient arrival pattern, which is(More)
In a previous paper, we developed an accurate simulation model of an Intensive Care Unit to study bed occupancy level (BOL). By means of accurate statistical analysis we were able to fit models to arrivals and length-of-stay of patients. We model doctors' patient discharge decisions and define a set of rules to determine the conditions for earlier or(More)
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