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Oxidative protein labeling in mass-spectrometry-based proteomics

• Julien Roeser, Rainer Bischoff, Andries P. Bruins, Hjalmar P. Permentier
• Analytical and bioanalytical chemistry
• 2010

Oxidation of proteins and peptides is a common phenomenon, and can be employed as a labeling technique for mass-spectrometry-based proteomics. Nonspecific oxidative labeling methods can modify almost… (More)

Boron-doped diamond electrodes for the electrochemical oxidation and cleavage of peptides.

• Julien Roeser, Niels F A Alting, Hjalmar P. Permentier, Andries P. Bruins, Rainer Bischoff
• Analytical chemistry
• 2013

Electrochemical oxidation of peptides and proteins is traditionally performed on carbon-based electrodes. Adsorption caused by the affinity of hydrophobic and aromatic amino acids toward these… (More)

Electrochemical oxidation and cleavage of tyrosine- and tryptophan-containing tripeptides.

• Julien Roeser, Hjalmar P. Permentier, Andries P. Bruins, Rainer Bischoff
• Analytical chemistry
• 2010

Electrochemical oxidation of peptides and proteins has been shown to lead to specific cleavage next to tyrosine (Tyr) and tryptophan (Trp) residues which makes the coupling of electrochemistry to… (More)

Chemical labeling of electrochemically cleaved peptides.

• Julien Roeser, Niels F A Alting, Hjalmar P. Permentier, Andries P. Bruins, Rainer Bischoff
• Rapid communications in mass spectrometry : RCM
• 2013

RATIONALE Cleavage of peptide bonds C-terminal to tyrosine and tryptophan after electrochemical oxidation may become a complementary approach to chemical and enzymatic cleavage. A chemical labeling… (More)

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