Julien Pineau

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AIMS The choice of resynchronization therapy between with (CRT-D) and without (CRT-P) a defibrillator remains a contentious issue. Cause-of-death analysis among CRT-P, compared with CRT-D, patients could help evaluate the extent to which CRT-P patients would have additionally benefited from a defibrillator in a daily clinical practice. METHODS AND RESULTS(More)
BACKGROUND Despite the major role attributed to myocardial vagal activity in left ventricular arrhythmogenesis in chronic myocardial infarction, the impact of infarction on left ventricular muscarinic receptor density remains unknown. METHODS AND RESULTS Left ventricular muscarinic receptor density was measured in vivo by positron emission tomography(More)
The aim of the study was to estimate the efficacy and complications of the first ablations of atrial fibrillation (AF) performed in a single teaching institution. The first 100 consecutive patients with symptomatic paroxysmal, persistent or permanent AF treated by application of radiofrequency in the left atrium, were included. In the patients with(More)
BACKGROUND Vagal innervation modulates the electrical stability of the left ventricle (LV) during ischemia. Thus, abnormal parasympathetic activity in myocardial infarction (MI) patients with primary ventricular fibrillation (FV) can account for their arrhythmic disorders. We evaluated LV muscarinic receptor density (B (max)) after MI in patients with(More)
The effects of chronic oral azimilide therapy on the ventricular defibrillation threshold (DFT) during ischemia are unknown. The effects of azimilide on defibrillation efficacy under ischemic condition were investigated in a closed-chest animal model. Azimilide (20 mg/kg/d) was administered orally for 7 days to 10 pigs (20 to 25 kg). The control group (no(More)
A 16-year-old boy was referred for radiofrequency ablation of an accessory pathway. He had not experienced palpitations, but a normal electrocardiogram was a prerequisite for enrollment in a professional soccer school. The electrocardiogram showed a PR interval of 0.10 second and wide QRS complexes suggestive of an accessory pathway. The case of a variant(More)
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