Julien Faccini

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Mitophagy is a critical cellular process that selectively targets damaged mitochondria for autophagosomal degradation both under baseline conditions and in response to stress preventing oxidative damage and cell death. Recent studies have linked alterations in mitochondria function and reduced autophagy with the development of age-related pathologies.(More)
An evaluation was made of the different protocols recommended by the Association Française de Normalisation (AFNOR) for assessing the sensitizing potential of chemicals in the guinea-pig. The methods studied were those of Magnusson & Kligman (J. invest. Derm. 1969, 52, 268), Maguire (J. Soc. cosmet. Chem. 1973, 24, 151), Maurer et al. (Agents & Actions(More)
The quantity of bone and osteoid has been measured in undecalcified sections of iliac-crest biopsy specimens taken from patients with fracture of the femoral neck. A control group of bone samples was obtained from post-mortem material. The 'Quantimet 720' image-analysing computer system was used to measure the area of bone and osteoid. An eye-piece(More)
Coronary artery disease (CAD) is the most prevalent cause of mortality and morbidity worldwide and the number of individuals at risk is increasing. To better manage cardiovascular diseases, improved tools for risk prediction including the identification of novel accurate biomarkers are needed. MicroRNA (miRNA) are essential post-transcriptional modulators(More)
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